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The condition was first recognized in 1930, and the name coined in 1967. It usually arises in those with longstanding diabetes, and affects 0.5% of the diabetic population in the U.S. in a 2:1 male-to-female ratio.1 It erupts spontaneously mainly on acral surfaces of the upper and lower extremities, but may also involve the trunk. 2019-12-06 Bullosis Diabeticorum. Bullosis Diabeticorum. J Gen Intern Med. 2017 Feb;32(2):220.doi: 10.1007/s11606-016-3802-3.

Contents. 1 Background; 3 Differential Diagnosis. 3.1 Vesiculobullous rashes; 4 Evaluation. 4.1 Rash Red Flags [1] 5 Management; 6 Kurdi AT. Bullosis diabeticorum. Lancet.

Lars Dahlin - Research Outputs - Lund University

Histology typically reveals a noninflammatory blister with separation in an intraepidermal or subepidermal location. Anchoring fibrils and hemidesmosomes tend to be decreased. The diagnosis of bullosis diabeticorum was made, and supported by a consulting endocrinologist.

Bullosis diabeticorum differential diagnosis

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The differential diagnosis must be made with epidermolysis bullosa, pemphigus, bullous pemphigoid, burns, erysipelas, arthropod bites and others. The histopathology exam is not typical.

For differential diagnosis, the presence of Raynaud phenomenon, plaque-type morphea, bullous morphea,. 978 Buschke, scleredema diabeticorum is.
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The exact etiology of bullosis diabeticorum is not known but it is thought to be Other differential diagnoses to be considered in these cases are friction blisters, and immunofluorescence pattern, the patient was diagnosed to have Bullous diseases of the skin and mucous membranes Vijaya B. Reddy, in Differential Diagnosis in Surgical Pathology (Second Bullosis diabeticorum ( 6.9). 2 Apr 2018 Dharmshaktu GS, Pangtey T. Giant bullosis diabeticorum over charcot knee. Fresh blood sugar levels sent along with total and differential counts, with males are commonly affected, and no specific tests are diagnosti Differentialdiagnos.

The co-occurrence of neuropathy and nephropathy suggests an underlying microangiopathy. The bullae are noninflammatory and asymptomatic, and they typically develop rapidly. Bullosis diabeticorum is an uncommon dermatological man - ifestation of diabetes. Bullae can appear spontaneously in diabetic patients.
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Affiliations. 1Department of Internal Medicine, Carolinas Medical Center, 1000 Blythe Blvd Suite 507, Charlotte, NC, 28203, USA. 2019-12-06 We present a case of bullosis diabeticorum.

Lars Dahlin - Research Outputs - Lund University

Lesions appear rapidly, primarily in an acral distribution in areas of otherwise normal-appearing skin, and range from a few centimeters to very large. Bullosis diabeticorum lesions heal spontaneously within 2–6 weeks and often recur in the same or different acral locations. Given that the blister contained clear sterile fluid, aspiration was not attempted so as to avoid secondary infection. Is bullosis diabeticorum a specific condition? What you should be alert for in the history Rapid and spontaneous development of one to several blisters, typically on the feet or lower extremities, without identifiable history of antecedent trauma.

We present this case to illustrate the rare occurrence of diabetic bulla in a diabetic patient especially with poor glycemic control. Bullosis diabeticorum is also known as bullous disease of diabetes and is a rare, distinct, spontaneous, non-inflammatory blister forming condition where the aetiology is not quite known.6 This was first reported in 1930 and there is a male preponderance.6 It was reported in nearly 2% of the diabetic population in a study done in India.7 They are common in the hands and the feet with the lower The differential diagnosis must be made with epidermolysis bullosa, pemphigus, We report a case of bullosis diabeticorum with blisters confined to the lower legs and feet.